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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7089d0f3b367607626292bbca2c2fcb54d4ade6bd014f8b6a316c2d1e9162b00' 
  AND token = 'GOyqr7syMzC/WAwYkk5pmK6xE4UzlB0+PcZxkQwR/O0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}