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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a53a7f3207d963862adfb719675e255970aec1b05ff4e48493519552831f90' 
  AND token = 'rf39uv/+gQ77fmCaPuZaqcN9bsOYuKgVvEUfQV1eFPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}