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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa6cadb311d1721ac7736aa4c2932081d51b01d0ff5de41432f9c2719f5ebe42' 
  AND token = 'ml1XWEvq79mXTBETYlE0alLqsO7wxI2/qZC5rMESAI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}