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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70db2b67b292b62668a6256d3d2dc985db3d4de75e4abff60b33cd5c17e1a12f' 
  AND token = '+4JGJCZ2zbYDjzQNUCdwbZ1ObOKMs2Fej9mS6rxJj9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}