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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef0bde6e8e3df5ddaf3477e6bb61b643b110541de8f693c87ede573fadf2b5cb' 
  AND token = 'Nwq0R/vzj7cywd8/VwvVvgwNsjxtQFAnuvLBtBBrCK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}