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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8226e6206410d3fed93975813a817acc7e8cb87e1b4ea91f3c7401f0365754ae' 
  AND token = 'eqbx6WBPhWqap86SXi7+PZiVmFJIUOizcjlm7S3d4VY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}