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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd48e56a8f7b9d6afa3c95a65b2110eb48ec971efdd41e6ee236a07b6875d427' 
  AND token = 'oXCrpgfGEm/cH0R9DXJf7XqG8ObwIhlxP18Uy/vuUmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}