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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1593248e4e7426097f25c193a7ee9326ff32dfce9cd2a6f9b03454d73b3893d5' 
  AND token = 'KVY38elKKe3pDKrnz1ZrMqOhLJaAnAiwqRHd7SlHNKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}