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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e0e889f63c9e348bc3c1941233d2a7513eb393f6ff8ea7dcede3ee7ca7ca572' 
  AND token = 'DPq/OiF33pe5FbbGuPpc+wIakcXIU14uKYGG3Vz/GB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}