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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd94b7f1f35bd3edf3395319610ced1bbbdda8b9326b7b60dc91c48029965c1e' 
  AND token = 'h0diTv8W9d4fI6VqK3gSLDYKRpo6EHVZfhJ2hcNxssg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}