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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20ce435f1c91dc29ee6fe0ee1d9500036a17d642eace6e53405b10a0f8a05499' 
  AND token = 'mUl+A7hrEPR+dRTTQZhLcFd4Ja9nVv9PzVjknYPjhw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00154

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}