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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f16906907aeeea1c18b39b8f8065f734bf0c2d1993fee0ffeb56a8609be41d' 
  AND token = 'JZXInvcD4QuRASowO9UQ7Yalrgj3BR0JHcIZ9njvjY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}