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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e647310838e2957ef48457fbc3216ad507f7da8ff8fd86d1c47737a393e5c82' 
  AND token = '2ur/LchvqSyf/qq6CYNwlt3vOHr/VR49eNOFUHQMaGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}