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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '297eaf61bfa32e869676f667512e778cc9d1be04d12a3337c6d2bd6091881eb4' 
  AND token = 'cuJOJehRqLoM6yqRu9uY+XmdXM0j7eZ4wE4JOL5Cuyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}