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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd63efb79405181e34f059fcd8b382dcadf8b2d3c2e71c3cee4b67b1c83c89ec4' 
  AND token = 'NEkJmYVb/RysACgt11SJhjZ5u9CVlU7EZ54q4HONjMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}