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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0818374c64bf121f62794864bb1d62a05661e3b846f25962eeacacb216a56d07' 
  AND token = 'gLBFRUWh+0zcuxMaedVg15/4msTBrsFmF9Dk1kI6xvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}