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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '825a67bfb2037b021ce68dd806959a234d7882d3f5ba04b1a1b222594fd48180' 
  AND token = 'PW5bbO9/vSQa/PYYnvDU6OVWtuUo9nd/jg0AfVQMptY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}