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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7fae6bb057b7cc2b21a01108a630c619bc395ea44091a0d72713e725663f35' 
  AND token = 'wP6oC4qjCMRDwsS2b6dtskyOoE8FSVda3IO1dPc4YVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}