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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26a065277b7bf9bdc8a1af25f387f9ec6062e133922516d3a7a12b8b790a3234' 
  AND token = 'DLMJ2YbOpURYmXHNxnUkCv+nL3bvR8/t8qOXCWd6G4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}