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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd307a64653b1d0b376d59ce0639a4d486d52a7cfe6d58f1d33f2f661603c5e7' 
  AND token = 'nuaczr4Jq4eejiPn8n30rZ2RkgzmtY1h66HPvANRu8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}