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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4e3833f31d8179247aaf97a995e6a6f3011845e31e1e7033e182a18a59500c7' 
  AND token = 'VsD32HqSoD18JEeaWGNQzl5ZhuD4JyB3WAR1OE9gB34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}