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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6b11fc130e79f8e6ed28f2bf403b4148232429908f64264fff1022fdf028e6' 
  AND token = 'Pvmp7XxxbuIu6LG6j2uKWa7GPrbhtKoC3D+dst2xGy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}