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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c2d05d8418d8f03f53b5fec22b9a59dee4e350596b41d5c73fc5856b810fcd' 
  AND token = 'MIu+KXw40Dn2TO6EP4PnLZUWUgVtKqo7XkaufX7OEdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}