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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da86fc58494ee3d40d1d9c5fc94149d87aca494f1318fa163564922ce6d995ae' 
  AND token = 'EQ4MxsLUutdRUWaT4Q8YxLZG10wA4iwnaCqQm8imDKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}