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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b64036156652f7db4d272fcaba2a7bf1ffc699f86adc2dd13aab85fe450a7b5' 
  AND token = 'i+NGgRIQ5PD/IHTMvsUn4NUOjuYdSORjI38OgT+5h6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}