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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fbd8ce21c2b5f3c3d15b6b83fb43eb0eda901b1aebf2abb52054e9531f9b376' 
  AND token = '3vmmVPIGxuKyYtIKT3BXLVjiik8ujnGYDN2unA8OAE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}