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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9e9051d28b634a181c891324512120272c6c5580da20a28b1cfc280bd157d5' 
  AND token = 'ZPHTnhOq8OtIE9wMgk3obxs2pQAhpRbkXXAOkw9PRFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}