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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2448fa22683080c52788f02840370fdd9f3d54a69646013470bf87ae94aea2a' 
  AND token = 'XWA22JMLqEjLqP4cmLFFPBsXxR3+x1AR0o573D4GGLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}