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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2a89a8c59eb8996306655d769f1a7ff44ffbf2ff19ac611a3486bffc540a90' 
  AND token = 'rJBiZsEqBCukxcY8lnYW5WbGV52fhe3n0lgDS0G+rF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}