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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4b600b2bd8889b843723bf1f7b42ce450a34d15ee775233daae3566287eac91' 
  AND token = '37+autpfLDCzDu6YtSiLhQO5E7oHRSQnSUExWkuRXDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}