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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f4817d9f502997147323106f5c63a5cd1ff91f5a4af594a8d1553361e108ea' 
  AND token = 'RuoTkNGx/M9HM2HA3BgrHL13tmI46vfK2aN5dptF0G8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}