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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ece31ad39c7660319c5b95757f4a9941084a84807393bd86513d23fe0b5f7b2' 
  AND token = '75d9VqGYaqncnnts2hXhBKPHPHmGy3c89QnSEOoCxSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}