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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '281099c10bed2490d1e9de7823ca537d0b5975efe28700d97be3c6ef2c10fffb' 
  AND token = 'NuLL6+NMGhRUK4nUjrjBgbvEVTsDtOuQ0ry9aHWLOos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}