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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa9a272ac3599e57f5cee124d9a6ab8333001a8e613d3886f6865d101dbdeffc' 
  AND token = 'hRuquRy8REHNTS9qQIy29tZQijsWHROHaFNV7AnQ7MY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}