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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c78223ca86c6c58b97f331798abceafb6d2305b0f44ef8ce1e1d949a4950a7' 
  AND token = 'Cs8fD4UVMoOkkQOHlAZETmzG2FDN7dMNX+992CU3zjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}