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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ae355567262e9b9fe8cec0a37174b53ce0161e027f81beed0488ed30059e653' 
  AND token = 'Hm0pbhSv96URkvjbpBuqe2oaVqBG0/vPxsmU2x+F5Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}