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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59125a3175e9794d6cac9cceb7647f909bd4ad66ea3bb85eac732cc9528eb2cd' 
  AND token = 'nWHGGE9h2T8iCYk/F/WcGAGJHpZ52ZwjJ5m9OTUrdm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}