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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d7d457a9cb3f8596f2652fb9c3148c0e174e9083b11d8fe995a53360a17208' 
  AND token = 'CvGdmtz8WCqNb+wmoIWgod5NW6tr/ohJgoxksGf375M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}