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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e54eb345c86329c40b770783892b7c09663a0a2e681e61f42c9224c6077c7e8' 
  AND token = 'GN5wJXDtMU5S3BpcSn2efxKy/DudxPTov7Fo5xeBa1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}