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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '838b9aef752bd15b873018e34f9737f57e6acd7c5634d34be0a9213d01ab6094' 
  AND token = 'XcRGcyYm/tr+BSfV2nL5i6P39XBgPDmcGwEIZ5BD8Ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}