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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1685c3a8646ad6c1a52d0eae07cdf53a4cfe1e5ee8e49750d29282ed7886b249' 
  AND token = 'ac2SBmvLEDOSHnJheiLt0h6RX8LJdnWiffGo+2bQteU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}