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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dede7e22ef55af692ae979120f91e2a3dad082ddd939c82da88dfaf3528aa105' 
  AND token = 'SxDr0XJ9mzfXtenfy/t6nGMpAnBzWzz4jhs73gl8c/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}