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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51c4a8180f671a7d5560d5b670c3e3879497df57e8e9049eb4ebd281389866c2' 
  AND token = 'rePTDVYHsS6O/4RnT+vOyiU4JYrbu5WStJB7xB9lf9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}