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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7af814df144f09781d43126c3719709df9a51bdf2c83df77ad5ca09c7246e069' 
  AND token = 'ez9kMPNkdyoMYom3hDS+1xHtMa9P5859BHaMc/UA3jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}