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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae7445cd2931acd56ae97446ea03316136f06b4f1a72503dfc6b0da298c97f4' 
  AND token = 'VR7dmuCe0E30hTwL628m/5k/p8WJOyELz23qLwu9+mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}