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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7459f4160b98fa2e4dd5dd939e3005597e89cd2cbf0870c7d6840424197a2919' 
  AND token = 'GH1KZI1K7qhu55kWBwL4dE24Aw5/yVwXfwX8GFZ9t18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}