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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '521039f17b2adbd349c9e353047b8357b06585aa1abd7f9e71445d968723c960' 
  AND token = 'DxRT091TH/8fQEr7XFKzz2Fa3bXmPWYXBlsu8wl7eiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}