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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36375afde756b31462a68e6fda6428798d1818ab7801801fc3049a6d4927c92f' 
  AND token = 'TkXJviEZS+0kfZ+yjnYc27ERPFd/eqnNV6NaYF0n9JA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}