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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c5e5e65b69b3b04907f36a9119b50586fd9a8676d0d0c536d5c78ff097d139' 
  AND token = 'ErXlQKvNPhLSOUa+eEDOxei/gAf1FoyDtbNeIXwW/XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}