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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd765c67792550ffb1c024b709e6e057eaebd95ce45104e9f4d5d4363620771a8' 
  AND token = 'NWdKanmxnfh+O7nE3LvYqq1NX+hxpIwDMEZVnx15rp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}